WEBINAR: How the Transmission of Alpha-Synuclein Elicits Parkinson’s Disease Pathologies
February 24 @ 12:00 pm - 1:00 pmFree
Presenter: Morgan Stykel, PhD Candidate
Parkinson’s disease is characterized by the presence of Lewy-bodies, which primarily contain the protein alpha-synuclein. In this Webinar, Morgan will describe how her research uses patient-derived stem cells to recapitulate vulnerable cell-populations to study disease. She demonstrates that a single alpha-synuclein mutation can elicit the accumulation and aggregation of proteins, characteristic of Parkinson’s disease. Morgan illustrates that alpha-synuclein spreads from cell-to-cell with emphasis on her most recent publication where she shows that extracellular vesicles (exosomes) might be facilitating this spread, triggering disease in previously healthy cells. She will also give us a sneak-peak at the ongoing research she is involved in.